Latest News & Research: 4 December 2018
This week: Yo-yo dieting associated with higher risk of death • Curry spice may enhance exercise performance • FILEX 2019 launches – and Network Members save
Yo-yo dieting associated with higher risk of death
Weight cycling is associated with a higher risk of death, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
Weight cycling, or the constant losing and gaining of weight (usually from diet), leads to adverse health outcomes. By some estimates, 80 percent of people who lose weight will gradually regain it to end up at the same weight or even heavier than they were before they went on a diet.
The Endocrine Society found this was because once an individual loses weight, the body typically reduces the amount of energy expended at rest, during exercise and daily activities while increasing hunger. This combination of lower energy expenditure and hunger creates a ‘perfect metabolic storm’ of conditions for weight gain.
In the 16-year prospective cohort study, researchers examined 3,678 men and women from the Korean Genome and Epidemiology Study and found weight cycling was associated with a higher risk of death. Interestingly, people with obesity who experienced more weight cycling were less likely to develop diabetes than other study participants. The health benefits of weight loss overshadowed the adverse effects of weight cycling for individuals with obesity looking to lower their diabetes risk.
Lead study author Professor Hak C Jang of Seoul National University in Korea said; ‘This study shows that weight cycling can heighten a person’s risk of death. However, we also concluded that weight loss as a result of weight cycling can ultimately reduce the risk of developing diabetes in people with obesity.’
Source: Endocrine Society
Curry spice may enhance exercise performance
New research suggests that curcumin, a main ingredient in curry, may improve exercise intolerance related to heart failure.
Curcumin, a chemical that comes from the turmeric plant, has been used as a traditional Asian medicine for centuries, primarily to treat gastrointestinal ailments and skin wounds. Studies increasingly suggest that the compound may prevent or limit muscle wasting associated with a number of health conditions, including heart failure.
People with heart failure have a reduced function of the left ventricle – the chamber of the heart that pumps blood out to the rest of the body – called reduced ejection fraction. A decreased ability to exercise (exercise intolerance) is another significant characteristic of heart failure. Previous research has found that higher than normal levels of oxidative stress, an imbalance of two different kinds of molecules that can result in cell damage, contribute to exercise intolerance in people with heart failure. Heart failure is also associated with lower than normal expression of antioxidant enzymes in the muscles, but the reason for this is unclear. Antioxidant enzymes both prevent and repair damage from oxidative stress. Boosting enzyme levels may improve exercise performance in people in heart failure.
Researchers from the University of Nebraska theorised that a reduction in the normal signalling of Nrf2, a protein that regulates the expression of antioxidant enzymes, may play a role in the impaired expression of antioxidant enzymes. They examined the effects of curcumin, which is known to promote activation of Nrf2, on a mouse model of heart failure with reduced ejection fraction. The study appears in the Journal of Applied Physiology.
The researchers found that expression of Nrf2 increased and levels of antioxidant enzymes improved in the animals with heart failure that were given curcumin. Both healthy and unhealthy mice also had improved exercise capacity.
Source: American Physiological Society
FILEX 2019 launches – and Network Members save
FILEX, Australasia's leading fitness convention, has revealed its 2019 program, which will be delivered alongside The Fitness Show between 12 and 14 April at the International Convention Centre in Darling Harbour, Sydney.
The program once again boasts an impressive lineup of local and international presenting talent, including behavior change coach Bobby Cappuccio, strength and conditioning expert Dr John Rusin, group training legend Marietta Mehanni, Brian St Pierre from Precision Nutrition, and Dr Emily Splichal – to name just a few.
New to FILEX in 2019 is the ‘Conversation’ series of practical sessions that provide the opportunity to share best practice and learn from fellow delegates in the areas of team development, sales and retention, while being facilitated by leading experts in those areas.
Also new to the event is the ‘Elevate’ series of lectures featuring 12 dynamic business owners and fitness leaders sharing one idea that made a real and significant difference to their industry success.
Registration is now open, with Early Bird rates available until 11 January. Network Members can save over $100 on registration by selecting Member rates – see HERE for details on pricing.